Detalhe da pesquisa
1.
Prediction of efficiencies for diverse prime editing systems in multiple cell types.
Cell
; 186(10): 2256-2272.e23, 2023 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37119812
2.
Recording of elapsed time and temporal information about biological events using Cas9.
Cell
; 184(4): 1047-1063.e23, 2021 02 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33539780
3.
Massively parallel evaluation and computational prediction of the activities and specificities of 17 small Cas9s.
Nat Methods
; 20(7): 999-1009, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37188955
4.
SynDesign: web-based prime editing guide RNA design and evaluation tool for saturation genome editing.
Nucleic Acids Res
; 2024 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38682594
5.
Sniper2L is a high-fidelity Cas9 variant with high activity.
Nat Chem Biol
; 19(8): 972-980, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36894722
6.
Magnetogenetics with Piezo1 Mechanosensitive Ion Channel for CRISPR Gene Editing.
Nano Lett
; 22(18): 7415-7422, 2022 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36069378
7.
Targeting mutant KRAS with CRISPR-Cas9 controls tumor growth.
Genome Res
; 2018 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29326299
8.
Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia.
Am J Hum Genet
; 100(3): 454-472, 2017 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28215400
9.
Paired D10A Cas9 nickases are sometimes more efficient than individual nucleases for gene disruption.
Nucleic Acids Res
; 46(12): e71, 2018 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29584876
10.
In vivo gene correction with targeted sequence substitution through microhomology-mediated end joining.
Biochem Biophys Res Commun
; 502(1): 116-122, 2018 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29787760
11.
Concise Review: Fate Determination of Stem Cells by Deubiquitinating Enzymes.
Stem Cells
; 35(1): 9-16, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27341175
12.
In Situ Pluripotency Factor Expression Promotes Functional Recovery From Cerebral Ischemia.
Mol Ther
; 24(9): 1538-49, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27455881
13.
Astroglial Activation by an Enriched Environment after Transplantation of Mesenchymal Stem Cells Enhances Angiogenesis after Hypoxic-Ischemic Brain Injury.
Int J Mol Sci
; 17(9)2016 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27649153
14.
Deep learning models to predict the editing efficiencies and outcomes of diverse base editors.
Nat Biotechnol
; 42(3): 484-497, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-37188916
15.
In vivo application of base and prime editing to treat inherited retinal diseases.
Prog Retin Eye Res
; 94: 101132, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36241547
16.
DNA double-strand break-free CRISPR interference delays Huntington's disease progression in mice.
Commun Biol
; 6(1): 466, 2023 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37117485
17.
Basic Principles and Clinical Applications of CRISPR-Based Genome Editing.
Yonsei Med J
; 63(2): 105-113, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-35083895
18.
High-throughput functional evaluation of human cancer-associated mutations using base editors.
Nat Biotechnol
; 40(6): 874-884, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35411116
19.
Application of prime editing to the correction of mutations and phenotypes in adult mice with liver and eye diseases.
Nat Biomed Eng
; 6(2): 181-194, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34446856
20.
In vivo outer hair cell gene editing ameliorates progressive hearing loss in dominant-negative Kcnq4 murine model.
Theranostics
; 12(5): 2465-2482, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35265220